Retrospective epidemiological study of vesivirus prevalence and natural transmission in cattle and horses in the USA

Screening of cattle sera: distribution of vesiviruses in terrestrial domestic animals. To broaden the knowledge of vesivirus occurrence and distribution dynamics in domestic livestock, we attempted the first extensive study in cattle to assess the distribution of vesiviruses by examining the... Ausführliche Beschreibung

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Weitere Verfasser: [advisor] ; [referee] ; [referee]
Format: Elektronische Hochschulschrift
veröffentlicht: Dresden : Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2004.
Schlagworte:
RVK-Notation: WF 4400 RNS-Viren
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041 |a eng 
037 |n urn:nbn:de:swb:14-1091175784031-25915 
100 |a Andreas Kurth  |e author 
700 |a Alvin W. Smith  |e advisor 
700 |a Axel Rethwilm  |e referee 
700 |a Alvin W. Smith  |e referee 
700 |a Gerold Barth  |e referee 
245 |a Retrospective epidemiological study of vesivirus prevalence and natural transmission in cattle and horses in the USA 
260 |a Dresden :  |b Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden,  |c 2004.  |9 (issued 2004-06-29) 
520 3 |a Screening of cattle sera: distribution of vesiviruses in terrestrial domestic animals. To broaden the knowledge of vesivirus occurrence and distribution dynamics in domestic livestock, we attempted the first extensive study in cattle to assess the distribution of vesiviruses by examining the seroprevalence. Cattle were chosen to be studied here, because this livestock is well characterized, they are suffering diseases with high percentages of unknown aetiologies and extensive animal data are available. Furthermore, several case reports exist on the isolation of vesiviruses from cattle. The objective was to evaluate the distribution of vesiviruses in cattle, correlate vesivirus infection with disease manifestations and estimate the possible impact on other animals and humans. Roughly seven hundred bovine sera from nine States within the United States were acquired and were tested for antibodies against vesiviruses. The sera tested were drawn from a total population of about 9 million cattle in nine States with a geographical distribution ranging from northern Alaska to tropical Hawaii. Screening of horse sera and tissue: correlation of vesivirus prevalence and mare reproductive loss syndrome (MRLS)? A newly emerged disease in horses was analyzed in the second half of this research project. Since all tests for the common toxic abortogenic agents had failed, a further nationwide investigation was initiated for uncommon and unknown infectious agent(s). Caliciviruses, and vesiviruses in particular, are a well established cause of abortion in swine and seals. Nevertheless, these viruses are not routinely tested for or diagnosed. When the Laboratory for Calicivirus Studies at Oregon State University was asked for specific help in this investigation, pertinent seroepidemiological studies were entrusted to me under the guidance of Professor Dr. Alvin W. Smith. After the first serological examination of equine blood samples from mares that had aborted in 2001 and an equal number of sera from unaffected animals from 2000 were examined, tissue samples from aborted fetuses and two other sets of blood samples from ETC-exposed mares from two experiments were acquired. These have been tested for vesivirus-antibodies and antigen. Furthermore, additional samples of ETC were tested for vesiviruses by RT-PCR. 
500 |a doctoralThesis 
856 4 0 |u http://nbn-resolving.de/urn:nbn:de:swb:14-1091175784031-25915 
856 4 1 |u http://www.qucosa.de/fileadmin/data/qucosa/documents/1163/1091175784031-2591.pdf 
650 4 |a Caliciviren 
650 4 |a Epidemiologie 
650 4 |a Natürliche Übertragungswege 
650 4 |a Pferde 
650 4 |a Prävalenz 
650 4 |a Rinder 
650 4 |a Serologie 
650 4 |a Vesiviren 
650 4 |a Calicivirus 
650 4 |a Cattle 
650 4 |a Epidemiology 
650 4 |a Horses 
650 4 |a MRLS 
650 4 |a Mare Reproductive Loss Syndrome 
650 4 |a Natural Transmission 
650 4 |a Prevalence 
650 4 |a Serology 
650 4 |a Vesivirus 
082 0 |a 570 
084 |2 rvk  |a WF 4400  |9 W  |9 WF 1000 - WF 9600  |9 WF 3000 - WF 4950  |9 WF 4000 - WF 4850  |9 WF 4400 
936 r v |a WF 4400  |b RNS-Viren  |k Biologie  |k Mikrobiologie  |k Virologie  |k Einteilung nach chemischen und physikalischen Eigenschaften  |k RNS-Viren 
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