Enhanced inhibition of clonogenic survival of human medulloblastoma cells by multimodal treatment with ionizing irradiation, epigenetic modifiers, and differentiation-inducing drugs, Journal of Experimental & Clinical Cancer Research (2016) 35:94 doi: 10.1186/s13046-016-0376-1

Background: Medulloblastoma (MB) is the most common pediatric brain tumor. Current treatment regimes consisting of primary surgery followed by radio- and chemotherapy, achieve 5-year overall survival rates of only about 60 %. Therapy-induced endocrine and neurocognitive deficits are common late... Ausführliche Beschreibung

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veröffentlicht: Universitätsbibliothek Leipzig, 2016
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